I'm in that exact situation, i can talk to new people and their family have them laughing and relaxed around me, partly as I'm there to help as the nurse on shift but also as is my natural persona.

The idea of opening a set is something I cant get into yet, I am new to PUA and only just finished reading game (so i been into this about a month now).

I been out with a wing and he got me to join a set he was in. At that time I can hit the ground running and work things easily.
I was even out last night with the same wing and an old friend of mine started talking to me and introduced his GF so i was chatting to him and getting everyone laughing. noticed some IOI's coming from her so ignored her for most part then started running a few things on her, he obviously wasnt happy about this and begins getting her attention back and AMOGing me, so i saw it as a time to practice a few ideas.

All in all it got to a point where my wing said to me that i held my own better than most and have good confidence in set... i just cant open sets

Wow, only if my only problem was opening... I have serious AA, like when I even think of starting a conversation with a girl, whether she sais something to make me respond and then start a conversation, or my mind will go blank and nothing will come out. For example, I was waiting for the bus and this HB7,5 sat next to me. I wanted to say something but my mind went totally blank, I couldn't think of anything to say. Luckily she asked my phone to call a friend so there I got the opportunity and talked to her.
I think my problem is every single problem registred by people who have AA combined: I can't open, and if by some reason I get to talk to a girl, I can't show her I'm interested nor make her interested in me. Also I have body language issues, they can easily spot when I'm nervous because my hands shiver and I start stuttering.
It's not that I don't know how to talk to girls, but I take a long time to feel comfortable, and what I want is to feel comfortable BEFORE I even start talking to her. Any tips?
Thanks, Xavi

I suggest reading The Power of Now by Eckhart Tolle.

Tolle basically talks about living in the NOW, and when you encounter AA you're not living in the NOW, but thinking about the PAST or the FUTURE.

When you encounter AA, your mind wanders off and you start thinking about painful PAST experiences or thinking about that she might reject you, thinking about the FUTURE. He talks about this more in depth in The Power of Now.

The next time you have AA, I will guarantee you will start thinking about your past or about the future, and if you do, examine your thoughts and watch them.

If its a past experience with a girl, examine your thoughts about what you did wrong, understand why it was wrong, and then don't do that. The girl rejecting you is an example of the future, but that is just an illusion that you just made up. You don't know if that illusion becomes a reality.

Don't think about it, just do, especially when it comes to talking to girls. What's the worst thing that could happen? Get rejected? Yup, that's the worst thing that could happen. But so fucking what? Move on. Shrug your shoulders, say "it was nice meeting you" and approach another girl.

Now, if you don't approach because you don't know what to say to open her, from the words of Nikki played by Ashton Kutcher in the movie Spread "...there's only one pick-up line. Everything else is cheese." He approaches a girl, maintains eye contact and says:

"Hi! What's your name?"

That's it! Spot a girl, if she sees you then maintain eye contact, walk up to her and ask her name. She will then tell you her name, you introduce yourself and, from there, you can say whatever the fuck you want.

you just have to realize that all the negative feelings or experiences that could possibly come from being rejected are completely overwhelmed by all the positive experiences and oppurtunities that will come out of it.

also as a side note , i dont know anyone who actually enjoys doing it but its just something that you need to do if you want to have any success. hell it could be extended to any part of life and a willingness to take risks and push yourself out of your own comfort zone.

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Seize the day

Thank you both, that really helped me, even if the next time I go out I still have this negative feelings, I am sure that they won't affect me as much as they did a few minutes ago.