Fluoxetine: Patient drug information
Copyright 1978-2012 Lexicomp, Inc. All rights reserved.
(For additional information see "Fluoxetine: Drug information" and see "Fluoxetine: Pediatric drug information")
Brand Names: U.S.
PROzac®;
PROzac® Weekly™;
Sarafem®;
Selfemra® [DSC]
Brand Names: Canada
Apo-Fluoxetine®;
CO Fluoxetine;
Dom-Fluoxetine;
Fluoxetine;
FXT 40;
Gen-Fluoxetine;
Mylan-Fluoxetine;
Novo-Fluoxetine;
Nu-Fluoxetine;
PHL-Fluoxetine;
PMS-Fluoxetine;
PRO-Fluoxetine;
Prozac®;
ratio-Fluoxetine;
Riva-Fluoxetine;
Sandoz-Fluoxetine;
Teva-Fluoxetine;
ZYM-Fluoxetine
Mexican Brand Names
Symbyax
Pharmacologic Category
Antidepressant, Selective Serotonin Reuptake Inhibitor
What key warnings do I need to know about before using this drug?
• The want to harm yourself is an unsafe sign of low mood (depression). It may last until your low mood is fully treated. If you are planning on harming yourself, call the ER (emergency department) right away.
• There is a chance of serotonin syndrome when using a migraine drug with this drug. The syndrome is caused by too much serotonin in the body. Signs include agitation, changes in blood pressure, loose stools, a fast heartbeat, hallucinations, upset stomach and throwing up, change in balance, and change in thinking clearly and with logic. Talk with the doctor.
• Sometimes drugs are not safe when you take them with other drugs. They can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.
• Please read the medication guide.
When is it not safe to use this drug?
• If you have an allergy to fluoxetine or any other part of this drug.
• Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
• If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this drug is started. Taking both at the same time could cause risky high blood pressure.
• If you are breast-feeding.
What is this drug used for?
• It is used to treat low mood (depression).
• It is used to treat obsessive-compulsive problems.
• It is used to treat mood problems caused by monthly periods.
• It is used to treat eating problems.
• It is used to treat panic attacks.
• It is used to ease long-term pain problems.
• It is used to treat anxiety.
• It is used to treat post-traumatic stress.
How does this drug work?
• Fluoxetine raises chemicals in the brain.
• With low mood (depression), sleep and eating habits may get better fast. Other signs may take up to 4 to 6 weeks to get better.
How is this drug best taken?
• To gain the most benefit, do not miss doses.
• Take in the morning.
• Take with or without food. Take with food if it causes an upset stomach.
• Take long-acting products once a week.
• Long-acting products: Swallow whole. Do not chew, break, or crush.
• There is a liquid (solution) if you cannot swallow pills.
• Those who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given.
What do I do if I miss a dose? (does not apply to patients in the hospital)
• Take a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.
• Do not change the dose or stop this drug. Talk with the doctor.
Are there any precautions when using this drug?
• If you have been taking this drug for many weeks, talk with your doctor before stopping. You may want to slowly stop this drug.
• If you have kidney disease, talk with your doctor.
• If you have liver disease, talk with your doctor.
• If you have seizures or are on seizure drugs, talk with your doctor.
• If you have bleeding problems, talk with your doctor.
• Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
• You may not be alert. Avoid driving and doing other tasks or actions until you see how this drug affects you.
• Avoid beer, wine, mixed drinks, or other drugs and natural products that slow your actions.
• Talk with your doctor before using other aspirin, products that have aspirin, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain drugs, or vitamin E.
• If you are taking any natural products, talk with your doctor.
• You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
• Tell your doctor if you are pregnant or plan on getting pregnant.
What are some side effects of this drug?
• Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
• Nervous and excitable.
• Headache.
• Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Not hungry.
• Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.
• Loose stools.
• Change in sex ability. This most often goes back to normal.
• Not able to sleep.
What do I need to watch for when using this drug?
• Change in the health problem being treated. Is it better, worse, or about the same?
• Dry mouth may cause more cavities. Take good care of your teeth. See a dentist often.
• Follow up with the doctor.
When do I need to call my doctor?
• If you think there was an overdose, call your local poison control center or ER right away.
• Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
• If you are planning to harm yourself or the want to harm yourself gets worse.
• Change in thinking clearly and with logic.
• Big change in balance.
• Agitation, twitching, sweating, or muscle stiffness.
• Very nervous and excitable.
• A fast heartbeat.
• Very upset stomach or throwing up.
• Very loose stools.
• Any bruising or bleeding.
• Any rash.
• Health problem is not better or you are feeling worse.
How do I store and/or throw out this drug?
• Store at room temperature.
• Protect liquid (solution) from light.
• Protect capsules and tablets from water. Do not store in a bathroom or kitchen.
General drug facts
• If you have a very bad allergy, wear an allergy ID at all times.
• Do not share your drugs with others and do not take anyone else's drugs.
• Keep all drugs out of the reach of children and pets.
• Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• In Canada, take any unused drugs to the pharmacy. Also, visit
http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/me ... eng.php#th to learn about the right way to get rid of unused drugs.
• Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
• Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
• Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.