Hi FancyLad welcome!
What do you mean by when you talk to girls you think you get IOI's out of them? What do they do to get your attention i mean? Do they do Kino (touching on the arm for example), do they laugh when you tell a funny story even if it aint? That stuff.
Also, just a bit of personal experience on my side in relation to getting good in game. You say you want to pull off at least 10 openers a night? You're just starting out so whats the hurry? I know from personal experience that your ambitious and you want to go out there and you want to game all the girls you like in the club or bar or wherever, but it takes time. Reading "The Game" gives you an awesome insight into what the seduction world and what the pickup community is like and what it offers, but you have to learn to crawl before you can walk.
If you're confidence is not up to par then it would be a good idea to overcome AA (approach anxiety) first and then take it from there, thats what i'm doing. 10 Openers per night is a good goal, but it might be a little overwhelming if you're just starting out and want to open in a club.
Finally, I've been in that situation many times were I get IOI's from a girl and I dont do anything about it, it makes you feel very doubtful about yourself and you end up question your own abilities and even yourself because you didnt have the courage to do anything, i'm sure alot of people have been there too. It actually happened this weekend when I started approaching to get over my AA and I was chatting to this girl, I knew what to do, but I knew I wasnt there to get her number or stay for long so I bounced.
Hope my advice helps you man
"Confidence doesn't come out of nowhere. It's a result of something... hours and days and weeks and years of constant work and dedication."