Hey Dude,
heres what I do, Say I'm in a line for macca's or something and there are some girls behind me and a friend, I turn around and ask "Hey weird question, but do you girls think my friend here looks gay?" and go with that opener, then after they give there opinion and the opener is over I normally just go with "So what are you girls up too" which they'll answer with "Not to much just seeing a movie" or something which will open them up to negs and the multiple thread theory which works a charm. Something like that works for me. Hope I helped!
macbeth