I have a chance to meet with my ex (Dominique) this weekend. She dumped me about two years ago for some asshole, but since then I learned a lot about Pick-Up.

I have a female friend (Anna) who was also her friend and she wanted to meet her just to make sure how is she. I know that Anna prefers my company rather than hers, so if I ask her to do as I say, she'll do it. (I'm 100% sure of it)
She knows nothing about me. She talked about me a few times with Anna. So I guess that wishes me luck.

Long story short: I want to fuck her and leave her. What would be the best way to do it?

I'm confused. Do you want to fuck your ex? Or her friend?

I think he wants to bang his ex, then leave her. Some people might say this is not a good idea as its coming from a bad place. I say go for it, game her as if she is just another girl, from the short post you made, doesn't sound like it would be to hard and if you have already slept with her that would make it a layup.

Odyn is spot on, just DHV show her how much better you are now and give her one for old times sake, but don't if there's any chance you'll fall for her again it didn't work out for a reason!

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Tempus neminem manet - Time waits for no one