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Its a lot easier if a girl is already checking you out, if so, just go up and tell her "lets go over here for a moment" or something.
If every PUA were to wait for the girl to check them out, he wouldn't get anywhere... You would only manage to approach 1 or 2 girls a night - if that.
Also opening a whole group in a very loud environment virtually impossible unless you are in great state.
In my opinion the best way to open in those types of clubs is going direct and try to isolate immediately... If her friends try and cockblock either just ignore them completely or be friendly but refocus your attention back on your target as soon as possible.
When you open you will have to speak 30% louder than you usually would and be able to show your intent - strong eye contact, good voice tonality, dominant body language. The girl should know you are speaking to her because you are sexually attracted to her.
Search "PUA Cold Approaching Tutorial (Infield Footage)" on YouTube to see a video on this.