Normally i stay away from opinion openers but i came up with this and think its pretty good (Will only last till December 21st)

(With your wing next to you)
Hey excuse me. I had a question you for you . me and my friend are arguing about how we think the world is gonna end on the 21st. I think theres gonna be a solar flare, and he thinks its gonna be the second coming (that gets a giggle or two)

Option 1 response (Most common)
HB: I dont believe its gonna end

PUA: (nudges wing smiles and says) Shes a non beleivers

Option 1 Reponse
HB: Says her opinion, its an easy ice breaker for both of you

Its always gotten a laugh from me then just go into a conversation

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FAIL PROOF PICK UP LINE: excuse my, im sorry to bother you but my father beats me, can i have your number.

this is a good one, i think ill use it with the one thats in your sig. both are great.

This opener definitely has an expiration date on it! Doesn't even matter if the world ends or not, this openers is useless after the 22nd.

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“Nothing is impossible, the word itself says 'I'm possible'!” ~Audrey Hepburn

I think this is a great opener despite having an expiration date, you can always use an other topic for your opener it doesnt have to discuss about the 21st in december, the pattern is still great.

P-Town. your sarcasm amuses me. Clearly your not sarcastic enough to see that my "fail proof pick-up line" is completely serious and how its everyday use gets me amazing amounts of pussy....

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FAIL PROOF PICK UP LINE: excuse my, im sorry to bother you but my father beats me, can i have your number.